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For example, the mTOR inhibitor rapamycin, which is a robust pharmacological intervention for extending lifespan in model organisms (Lamming et al, 2012), also prevents chemotherapy-induced infertility (Goldman et al, 2017)

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The results of the fed-batch cultures are shown in Fig

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Also, data from vitiligo patients in in vitro mechanistic study ( In vitiligo patients, these three factors (hyper-reactive IS, chronic OS, and deficient EAS) interact in an interdependent and reciprocal way