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Figure 5 In another approach, biotinyl-spermine (biotine-spm) and in vivo expressed E

Measuring only blood concentration misses the tissue compartment where biological effects actually occur

These above processes lead to the production of PLOOH and the accumulation of 4-hydroxynonenal or malondialdehyde, which are oxidative damage-induced lipid peroxidation biomarkers

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Recent research has extensively explored the link between lactylation and aging, beyond neurodegeneration, in conditions like intervertebral disc degeneration [74] and skin aging [75]