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Oxidative Stress and Therapeutic Development in Lung Diseases

Proc Nati Acad Sci 102, 52565261.Google Scholar Motohashi, N, Mori, I & Sugiura, Y

revealed that overexpression of ZIP6 or elevated intracellular zinc levels in cancer cells substantially activated the PI3K/AKT and MAPK/ERK signaling, which upregulated downstream oncogenes such as MMP1 , MMP3 , MYC , and SLUG