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Obligate biotroph parasitism: can we link genomes to lifestyles

NOX1 and DUOX2, prevalent along the GI tract, produce substantial ROS quantities, essential for an oxidative burst employed by innate immune cells to eliminate phagocytized pathogens (8, 9)

Oxidative stress itself suppresses mitochondrial function, which contributes to diminished neuroplasticity and neurogenesis, with increased apoptosis and neurodegeneration in BD [23, 25, 81]