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Transient tear hyperosmolarity disrupts the neuroimmune homeostasis of the ocular surface and facilitates dry eye onset

10.3390/ijms13044831 9 BeauregardA.-P.HarquailJ.Lassalle-ClauxG.BelbraouetM.Jean-FrancoisJ.TouaibiaM.et al (2015)

doi: 10.1016/j.ecoenv.2020.111887 22

doi: 10.1038/s41401-022-00953-z 80 SunQHongZZhangCWangLHanZMaD

Other congeners such as ritlecitinib (JAK3 inhibitor), brepocitinib (JAK1 and TYK2 inhibitor), and JAK1/3 inhibitor (ATI-50002), combined with phototherapy are also under trial