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Additionally, KD has been shown to suppress apoptosis in hippocampal neurons by downregulating the AMPK pathway and reducing HSP70 expression [51]

Mediators released from granulocytes during inflammatory reactions up-regulate the expression of adhesion molecules on endothelial cells ( Chapter 3 ) and further enhance the tendency for sickle red cells to arrest during transit through the microvasculature

Carnitine is essential for optimal human health , and has been identified by researchers as a "quasi-vitamin" because of its absolute necessity for optimal metabolic function

However, the regulatory mechanism of ferroptosis has not been fully elucidated and the investigation still faces challenges

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