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Anti-Doping Agency education article CDC Vaccine Administration Guidelines Subcutaneous route technique (angle, site selection, no aspiration) Experimental & Molecular Medicine (2025) Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes (Kong BS, Lee H, LYi S, et al.) MedlinePlus Medical Encyclopedia (2023) Subcutaneous (SQ) injections Patient instructions for proper technique Additional Research and Background These sources provide related context and are not presented as support for a specific statement above

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*Correspondence: Zhigang Ren, [email protected] Yu, [email protected] These authors have contributed equally to this work This article was submitted to Signaling, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

VEGF promotes angiogenesis, the formation of new blood vessels