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Antioxidant Interventions in Hashimoto's: The Clinical Evidence While direct human clinical trials of oral glutathione supplementation specifically for Hashimoto's thyroiditis are still limited, the evidence from related antioxidant interventions is highly instructive: A comprehensive systematic review and meta-analysis published in Thyroid (2024) - conducted by researchers at the University of Bern, Switzerland - analyzed 35 randomized controlled trials (RCTs) involving 2,358+ participants with Hashimoto's thyroiditis

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In contrast, three proteins decreased collectively and significantly by at least 0.67-fold in OA-treated cells (Figure 1D), while the abundance of another protein (GSTA1) was further reduced on the fifth day of treatment (0.89-fold and 0.39-fold, respectively, compared to the control)

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