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Antioxidant activity of Aloe vera and prediction of interaction mechanisms on ROS1 kinase and collagenase receptors

Cells were collected 48 h after transfection for analysis of apoptosis, stained with FITC Annexin V Apoptosis Detection Kit I ( BD biosciences, USA), and analyzed by flow cytometry

These impairments drive autophagic and endosomal abnormalities

VMAT2 exploits this H gradient via protonmonoamine exchange to actively transport cytosolic monoamines into the vesicle against their concentration gradient, enabling vesicular storage and subsequent regulated neurotransmitter release