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Heat-induced protein denaturation Toxic proteins are widely distributed in seedderived TCMs across multiple families, including Euphorbiaceae (e.g., Crotonis Fructus , Badou

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[14] [15] [16] In the final step of the biosynthesis, two molecules of 6,7-dimethyl-8-ribityllumazine are combined by the enzyme riboflavin synthase in a dismutation reaction