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J Clin Neurol (2006) 2(4):2527.10.3988/jcn.2006.2.4.252 64 BoontanrartMHallSDSpanierJAHayesCEOlsonJK

Through epigenetic modification, control of transcription, RNA processing and translation, lncRNAs have been shown to play crucial roles in various biological processes such as cell growth, metabolism, differentiation and apoptosis ( In previous study, we reported that lncRNA Fantom3_F830212L20 and Nqo1 were co-expressed lncRNA and protein-coding gene, and both of two were significantly up-regulated in lung tissues of chronic CS-induced COPD mouse model, 16HBE cells and A549 cells exposed to CSE treatment when compared to their controls ( Materials and Methods Animal Experiments C57BL/6J male mice (68 week old) were purchased from Guangdong Medical Laboratory Animal Center (Guangzhou, China)

The researchers also found that n(CAT) persists in circulation for a longer duration than the native enzyme

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EGPA, eosinophilic granulomatosis with polyangiitis