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doi: 10.1111/acel.2015.14.issue-5 Summary Keywords oxidative stress, sperm dysfunction, reactive oxygen species, DNA fragmentation and male infertility, male infertility Citation Wang Y, Fu X and Li H (2025) Mechanisms of oxidative stress-induced sperm dysfunction

1bk), further supporting that the direct interaction of MeCbl with GSDME prevents its cleavage of the latter and represents the primary mechanism of MeCbl in inhibiting pyroptosis

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The tissues were then centrifuged at 5000 rpm for 5 minutes to collect the supernatant in Eppendorf tubes, and stored at -20 C for biochemical tests

This can sometimes lead us to a genetic mutation called methyl-tetrahydrofolate reductase, or MTHFR