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doi: 10.3389/fmed.2020.00057 Received 03 January 2020 Accepted 06 February 2020 Published 25 February 2020 Volume 7 - 2020 Edited by Christian Perronne, Assistance Publique Hopitaux De Paris, France Reviewed by Allison DeLong, Brown University, United States

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These variants have varied levels of function, ranging from partial to complete loss of function

For example, 6% of those 3 months) unexplained gastrointestinal symptoms (e.g., pain or diarrhea), reflecting impaired regeneration of epithelial cells