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Here we show that a single administration of GLP-1 or GLP-1MK-801 elicits comparable reductions in the blood glucose levels in DIO mice, whereas equimolar MK-801 monotherapy does not acutely affect glycaemia (Fig

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Based on studies of plants deficient in enzymes such as ascorbate peroxidase (APX) and catalase (CAT), accumulation of GSSG is quite closely related to the intracellular availability of H 2 O 2 (Rizhsky et al., 2002

These changes can be reversed by Fer-1, indicating that iron overload induced ferroptosis in HH mice, and suggesting targeting ferroptosis could be a promising strategy for treating hemochromatosis-related injury