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While it activates the GLP-1 receptor, Zepbound also targets the GIP (glucose-dependent insulinotropic polypeptide) receptor, making it a dual receptor agonist

Stone, Functional magnetic resonance spectroscopy in patients with schizophrenia and bipolar affective disorder: Glutamate dynamics in the anterior cingulate cortex during a working memory task, Eur

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Normal saline (0.9% sodium chloride) can be used to dilute a peptide after reconstitution (e.g., diluting an acetic acid reconstituted IGF-1 LR3 solution to raise the pH) but should not be used as the primary reconstitution solvent for lyophilized peptides