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The metabolism of these compounds by GT positive tumor cells should produce high local concentrations of bioactive and membrane permeable metabolites that would then block tumor cell proliferation and eventually tumor growth

pinicola fruiting bodies (Kozarski et al

In the case of NK cells, glycolysis and OXPHOS play important roles in maintaining their cytotoxicity, as indicated by the inhibition of these processes leading to diminished expression of IFN and Fas ligands