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Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation

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For example, the dysregulation of translational regulators (Bhat et al., 2017), the overproduction of enzymes (DeBerardinis and Chandel, 2016) or changes in the cellular microenvironment such as a lower pH (Kato et al., 2013) can be facilitated for selective therapeutic drug delivery

5e), which resulted in lower tumor burden and longer survival compared to mice treated with control CAR T cells (Figs

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