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Description

(+)- tocopherol succinate (-TOS), a succinate ester of (+)- tocopherol, can induce apoptosis of NB4, NB4-R2 (ATRA-resistant) and primary APL cells

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One such pathway involves the conversion of NADPH to NADH via the action of glutathione reductase

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Some studies suggest that taking 2.4 to 6 grams of CLA daily over 612 months may be associated with modest reductions in body fat (around 1.3kg), although results vary and more evidence is needed

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