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Description

DNA repair systems, of course, protect against damage to DNA, but over time, unrepairable damage may accumulate

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Phenolic compounds exhibit a anti-genotoxic activity with many mechanisms such as inhibition of promutagens, induction of detoxification mechanism, blocking of free radicals, scavenging of reactive oxygen species, and neutralization of oxidative stress and inhibition of DNA cleavage 66

On the other hand, the hormone status and other metabolites levels, such as serum 25(OH)D in women younger than 30 years, are lower than that in women 30 years and older (Reference Nakamura, Nashimoto and Matsuyama45)