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Cells were loaded with MitoTracker Red dye (Excitation/Emission: 579/599 nm) at 100 nM final concentration (37 C for 15 min) mounted in Live Cell Imaging Solution (Thermo Fisher), and viewed under a laser confocal microscope (LSM 510

Phytochemistry 71:338350 Droog F, Spek A, vanderKooy A, deRuyter A, Hoge H, Libbenga K, Hooykaas P, vanderZaal B (1995) Promoter analysis of the auxin-regulated tobacco glutathione S -transferase genes Nt103-1 and Nt103-35

Brain GSH Levels in Neurodegenerative Diseases Ageing is one of the risk factors involved in neurodegeneration, and both increased oxidative stress and decreased GSH levels are important risk factors for age-related neurodegeneration in the CNS [29]

Research has recognized ferroptosis as a possible pathogenic mechanism associated with lumbar disc herniation, although detailed mechanistic investigations remain scarce