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Besides, zinc is also involved in the inhibition of invasion and adhesion in malignant prostate cancer cell through several ways: strongly prevents the enzymatic activity of prostate-specific antigen (PSA) and suppresses the invasion of LNCaP cells, 360 reduces the expression of vascular endothelial growth factor (VEGF), 361 interleukin (IL)-6, IL-8, matrix metalloproteinase-9 (MMP9), intercellular adhesion molecule-1 (ICAM1), diminished the activity of urokinase-type plasminogen activator and aminopeptidase N (AP-N) 362 (Fig

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Structure of mPEG-DSPE PEGylated Liposomes for Tumor Targeting PEGylated liposomes take advantage of the EPR effect of tumors to increase the accumulation of drugs at the tumor site with their own long circulation properties, achieving passive targeting of tumors

10.1016/j.taap.2016.08.027 Toxicol Appl Pharmacol