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4.2.1 Energy crisis and purine metabolism disruption Formic acid, a metabolite of MA, inhibits cytochrome c oxidase (Xiao and Zhu, 2025), leading to mitochondrial dysfunction and ATP depletion, which in turn disrupts purine metabolism

NGF plays a critical role in cavernous nerve regeneration, facilitating reflex erectile recovery after nerve injury [89]

[3] Gmez-Manzo, S

A reason for the reduced production of antibodies could be the notable decline in the presence of long-lived antibody-secreting plasma cells that recirculate within the bone marrow in older adults [372]

1b), we favor an attack of roGFP2 at the glutathione sulfur atom as the most likely roGFP2 oxidation pathway (reverse reaction from mechanism (ii) or (iii) from Fig