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doi: 10.3389/fphar.2025.1656316 Received 29 June 2025 Accepted 12 August 2025 Published 22 August 2025 Volume 16 - 2025 Edited by Barbara Ruaro, University of Trieste, Italy Reviewed by Mohammad Irshad Reza, North Dakota State University, United States Burak Okyar, Ministry of Health, Trkiye Jacopo Simonetti, Universit cattolica del Sacro Cuore di Roma, Italy Updates Copyright 2025 Zhang, Zhang, Hu and Zhang

To diagnose B12 deficiency, doctors typically run several tests, especially a blood test (plasma/serum)

Dietary supplements L-glutamine, L-cystine, glycine aminoplusglutathione are no substitute for a balanced and varied diet and a healthy lifestyle

Users say this delivery method gives quick results like more energy and better focus, though independent scientific proof remains limited

Senile plaques (extracellular depositions) and neuronal tangles (intracellular accumulation of misphosphorylated tau protein), are the main histopathological hallmarks of the AD, critical for post-mortem diagnosis