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Preincubation with 5 ng/ml TGF for 24 h increased SMA-positive cytoplasmic staining, which is indicative of myofibroblast transdifferentiation (Fig

Impairment of aryl hydrocarbon receptor signaling promotes hepatic disorders in cancer cachexia

In the present study, the impact of low-dose testosterone gel administration on the plasma lipidome was investigated short-term, over a 28-day period, on matched healthy young female subjects (n = 14, premenopausal, aged 2237) using a comprehensive and quantitative mass spectrometry (MS)-based lipid profiling

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Mutational changes of the +4 and +5 residues abolished the interaction of the motifs with the AR, which further confirms the importance of intact +1, +4, and +5 hydrophobic amino acids in the motif 83