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Their therapeutic potential lies in leveraging diet-microbiota-metabolite crosstalk to overcome ICI resistance, though clinical translation is constrained by interindividual microbial heterogeneity, inconsistent metabolite production, and the need for context-specific targeting (263)

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Excitingly, preclinical trials have shown that dietary compounds have made significant progress in counteracting chemotherapy drug resistance and improving the effectiveness of both radiotherapy and chemotherapy for tumors has been made

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All Lyme disease test kits that are FDA-approved are based on a single strain of a single species of borrelia