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Any degradation, whether its hydrolysis, oxidation, or aggregation, can compromise that shape and, consequently, its efficacy

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doi: 10.1016/j.jss.2016.08.011 149 JezekPDlaskovaA

Considering the functional requirement for plasma membrane localization of this heptahelical transmembrane receptor, we confirmed GABBR1 expression was also elevated in subcellular fractionation of overexpressing A549 and H358 cells by Western blotting (Figure 4C)

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