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Endocrine disorders, particularly diabetes, are often comorbid with neurological conditions such as Parkinson's disease and dementia

Main Hormonal Regulators of SomatotrophsGHRH and Somatostatin Two brain (hypothalamus)derived modulating factors, the stimulator GHRH and the inhibitor somatostatin (70), act as the primary central regulators of both synthesis and secretion of pituitary GH ( Figure 1 ) (1, 7, 14, 15, 20, 21, 26, 34, 38)

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As a group, these compounds stimulate the production and release of HGH

In addition, lipoxygenase (LOX) could oxygenate PUFA-PE to produce fatty acid hydroperoxides, thus driving cell ferroptosis ( 3 The metabolites of TCM drugs targeting ferroptosis for cancer therapy 3.1 Alkaloids Solasonine, a steroidal glycoalkaloid derived from Solanum nigrum L