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Research applications include investigation of skin biology mechanisms, tissue repair processes, cellular regeneration pathways, and the development of combination approaches for dermatological research

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This may lead to autophosphorylation of a bidentate docking site in the carboxy-terminal cytoplasmic tail (tyrosine residues Tyr1349 and Tyr1356)

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Under normal circumstances, collateral vessels enlarge gradually over weeks to months in response to sustained ischemia