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The half-life of 159 to 195 hours means there is some flexibility, a day early or late will not ruin the protocol, but regular weekly timing produces the most stable plasma levels

KPV (1,000 mcg) is a naturally occurring tripeptide composed of lysine (K), proline (P), and valine (V) representing the C-terminal sequence of alpha-melanocyte-stimulating hormone (-MSH), retaining its potent anti-inflammatory and antimicrobial properties without melanogenic effects

Studies on specific populations could lead to a failed validation of potential metabolite biomarkers in MS, thus impeding their diagnostic and therapeutic clinical application

This article is part of the Topical Collection on Preeclampsia Rights and permissions About this article Cite this article Gunaratne, M.D.S.K., Thorsteinsdottir, B

Galea, 2021)