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Decreased expression of GSH synthesis leads to low free GSH levels, resulting in elevated ROS, immune dysfunction, and increased disease severity in COVID-19 patients 592

As used herein, the wavy lines on formulas represent the attachment sites between each part (Ab, L, Z, X and D) of the ADC of the disclosure

Diagnostic accuracy of holotranscobalamin, methylmalonic acid, serum cobalamin, and other indicators of tissue vitamin B12 status in the elderly

10.1016/j.cca.2012.12.007 46 YaffeK.BlackwellT.KanayaA

Copper serves as an essential cofactor for over a dozen so-called cuproenzymes, including superoxide dismutase (SOD) for antioxidant defense, lysyl oxidase for collagen cross-linking, and cytochrome c oxidase for cellular respiration