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The antioxidant activity of catechin could be attributed to either its radical scavenging and metal-chelating properties, or its modulatory effect on transcription factors and enzymes [118]

A significant decrease in sperm quality was found in Nrf2 knockout mice [93]

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Interest has focused on substances with antioxidant potential such as: vitamin E, carotenes, flavonoids, resveratrol, epigallocatechin gallate, curcumin, Co-enzyme Q10, melatonin and edaravone as useful agents in the management of this disease (Table 1)

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