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For prepubescent females or patients with malignant tumors who cannot postpone radiotherapy or chemotherapy, cryopreservation and transplantation of ovarian tissue represent the sole method for fertility preservation (60)

The biogenesis and precise control of RNA m6A methylation

Arya, R., et al

Considerations for Potential Applications of the AOP (optional) Addressess potential applications of an AOP to support regulatory decision-making.This may include, for example, possible utility for test guideline development or refinement, development of integrated testing and assessment approaches, development of (Q)SARs / or chemical profilers to facilitate the grouping of chemicals for subsequent read-across, screening level hazard assessments or even risk assessment

3 Metabolic pathways altered in multiple myeloma MM cells employ specialized metabolic programs that differ from neighboring, untransformed somatic cells to sustain their extraordinary anabolic and catabolic needs (6, 4245)