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Absorbance was measured with a microplate reader (Epoch, BioTek Instruments, VT, USA)

This might be particularly relevant in activities such as phagocytosis, where cells ingest harmful particles, and inflammation, a critical response of the immune system to infection and injury

However, you can still get plenty of B12 on a vegan diet with help from a supplement, or in sources like fortified breakfast cereals

Some research suggests that high-dose oral B12 supplements work just as well as B12 shots for raising B12 levels in people with a deficiency

This effect is notably reduced in adipocytes from obese individuals, suggesting that impaired cGMP signaling may contribute to the insulin resistance observed in T2DM