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The KD was also shown to increase anti-inflammatory responses in glaucomatous mice, evidenced by increased expression of Arginase 1, a marker of neuroprotective anti-inflammatory microglia, as well as increased expression of the anti-inflammatory cytokine IL-4 in retinas and optic nerves (40)

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Its three-amino-acid form belies a mechanistically sophisticated action direct intracellular NF-B inhibition delivered via a gut-specific transporter that self-upregulates in inflamed tissue

For the effect of GSH on PAAD growth, cells were incubated with BSO (Sigma, USA) for 12 hours or GSH (Sigma, USA) for 3 hours before transfection

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