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The depletion of brain GSH has also been observed from both autopsies as well as in vivo MRS studies with aging and varied neurological disorders (Alzheimers disease, Parkinsons disease, etc.)

Metabolic pathways of moclobemide include mainly oxidative attack on the morpholine moiety [182]

In breast cancer, AMPK displays perhaps the most well-known dual roles, with its function determined mainly by tumor stage, phenotype and microenvironmental situations (178)

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In ovarian cancer, the levels of Gln, glutamate, and GSH in the cisplatin-resistant cell line A2780cis were significantly higher than those in the A2780 cells, while the expression of GS decreased