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Individual peptide monotherapy groups and BPC-157 alone and TB-500 alone at the same doses used in the combination group and are essential for determining whether combination effects are additive, synergistic, or less than additive relative to each individual peptide

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Regardless of the NOS isoform, the biochemical pathway to produce NO is the same and all require cofactors including NADPH, flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN), tetrahydrobiopterin (BH 4 ) and ferrous iron (Fe 2+ )