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3.1 Mechanisms of ferroptosis in ischemic stroke Stroke, defined as an acute focal CNS injury caused by vascular events, results in neurological deficits

A confirmed B12 deficiency is diagnosed through a blood test measuring serum B12 levels, along with tests for MMA and homocysteine, which become elevated in deficiency cases

This approach is based on the physical adsorption of a binding agent onto a surface through forces such as electrostatic interactions, hydrophobic interactions, or hydrogen bonding [79,80]

Oxygen to be transported efficiently by erythrocytes depends on the presence of hemoglobin, a protein capable of binding oxygen through its central iron atom (128)