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DOI: 10.1098/rsif.2019.0547

Direct answer: Mild digestive symptoms like nausea, constipation, or bloating may continue but often improve in severity

The generated tubuloids showed active transepithelial transport function and were used to model several diseases, including BK virus, Wilms tumor, and cystic fibrosis, showing the great potential of this culture system for disease modeling and the possibility to use it for drug screening (Schutgens et al

This signalling may disrupt cancer immune surveillance, promoting immune evasion and resistance to immunotherapies, including immune checkpoint blockers