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Administered at a dose of 360 mg/kg for 14 days, the extract markedly reduced IBA-1, IL-1, A1-42, and phosphorylated tau (p-tau) levels, highlighting its anti-inflammatory and neuroprotective properties (Wang Y

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Additionally, a 2020 observational study published in the Journal of Dermatology and Dermatologic Surgery identified correlations between periorbital hyperpigmentation (dark circles under the eyes) and low serum ferritin levels an early indicator of iron deficiency

Although metabolic phenotype in HF can perceptibly vary according to etiology and HF stage as alterations progressively set in [124], studies in human and animal HF models revealed typical metabolic alterations in advanced HF