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Phenytoin is an estrogen receptor -selective modulator that interacts with helix 12

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Although Cp GUS and Ec GUS had similar preferred substrates, C p GUS was the superior catalyst in terms of its ability to hydrolyze the bulky substrate 17 , which may be a consequence of the presence of F448 or M448 in loop 5 of Ec GUS and Cp GUS, respectively

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