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Behnammanesh G, Durante GL, Khanna YP, Peyton KJ, Durante W (2020) Canagliflozin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration: Role of Heme Oxygenase-1

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Tcr-triggered extracellular superoxide production is not required for T-cell activation

Rac1 can bind to WRC, inducing a conformational change that promotes the activity of the Arp2/3 complex, leading to F-actin nucleation and lamellipodia formation

Furthermore, variants in COL3A1 , such as the p.Gly637Ser mutation, have been linked to collagen synthesis abnormalities in a single family with the autosomal dominant hEDS phenotype that was identified which led to reduced collagen secretion and the over-modification of collagen [5,73]