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Individuals with Certain Medications : Long-term use of certain medications, including proton pump inhibitors (PPIs) for acid reflux and metformin for diabetes, can reduce Vitamin B12 absorption

Botox is an off-label treatment (not officially FDA-approved for this use but supported by research and clinical practice) that can help by blocking pain signals and relaxing the muscles around the affected nerve

It works closely with folate to ensure proper cell division

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1 Introduction Mitochondria, as quintessential organelles in eukaryotic cells, serve dual roles as cellular energy suppliers and key regulators of calcium homeostasis, oxidative stress responses, and apoptotic signaling pathways (Mattson et al., 2008