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However, most research on the safety of NSAIDs has focused on foetal malformations and nephrotoxicity in children 13,59

& Strange, R

Sumpton D, Kelly A, Tunnicliffe DJ, Craig JC, Hassett G, Chessman D, et al

LSS contributed significantly to spinal surgeries in the US: Within a year of diagnosing lumbar degeneration, 5.9 out of every 100 patients had a lumbar fusion procedure

Key risks include lean muscle mass loss, heart rate elevation, pancreatitis, gallbladder disease, hypoglycaemia, and acute kidney injury from dehydration