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As a note, -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate receptors are important for the initial stages of remyelination after experimentally induced demyelination, where the binding of glutamate released from active axons within the lesion promotes proliferation, survival and differentiation of OPCs during development and adulthood in rodents (Gautier et al., 2015

Endoplasmic reticulum: a metabolic compartment

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Polymorphisms in MTHFR (most commonly C677T and A1298C) can reduce this enzymes efficiency, leading to lower methylfolate levels and impaired methylation

The ligaments then collapse into droplets under the influence of the surface tension