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The proinflammatory immune response with high levels of inflammatory processes which is present in most infected cases is associated with hypercoagulable state [10]

Given that the key role of GPX4 for the maintenance of neuronal function, selective deletion of GPX4 in the brain contributes to cognitive impairment and neurodegeneration ( Collectively, our present work shows that lapatinib, a well-known anti-cancer drug, protects brain against epileptic seizures

To address this knowledge gap, here we develop a mathematical model that incorporates the most essential molecular elements for NADPH production, ROS generation, GSH synthesis, and detoxification of ROS by GSH in the outer retina, formed by photoreceptors and the RPE (see Fig

Ballatori, N., Krance, S

Ferroptosis: mechanisms, biology, and role in disease