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DAgostini F, Balansky R, Pesce C, et al

Methazolamide: This lipophilic acetazolamide analog exhibits remarkable advantages over acetazolamide in preventing AMS due to its higher lipid solubility, lower plasma protein binding, reduced renal excretion, and fewer side effects

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Labwork at that time was notable for an elevated uric acid of 10.6mg/dl (reference range: 3.5 - 8.5 mg/dl.) Out of concern for TLS precipitating hyperuricemia in the setting of a high-grade tumor in addition to starting a new chemotherapy regimen, the patient was additionally given 10mg of rasburicase and started on 300mg of allopurinol daily

Storage conditions Store at room temperature, in a cool, dry place protected from light