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Additionally, in a randomized, placebo-controlled crossover trial of older adults with impaired endothelial function, MitoQ supplementation was safe and significantly improved vascular endothelial function, reduced arterial stiffness in those with elevated baseline levels, and lowered plasma oxidized LDL [206]

the differential response of the glutathione and NADP redox states to oxidative challenge in glr1 and wild-type yeast and during reoxygenation in plants, the behaviour of NERNST closely mirrored that of the well-established E GSH sensor, roGFP2-Grx1, and particularly that of a free roGFP2, which can equilibrate with the glutathione redox couple via the action of endogenous glutaredoxins, and was opposite to that of the NAPstars

L.KattaR.LyuX.et al (2021)