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Low-dose radiation conditioning enables CAR T cells to mitigate antigen escape

The dosage of sertraline used in our animal model is equivalent to the dosage received by patients for the indication of depression

To induce the depletion and impotence of effector T cells, the peripheral cells, CAFs and MDSCs, and T cells can be induced to express immunoglobulin and PDL1 on their surfaces, and secret related factors such as IDO and TGF- (72)

Those who receive enough B12 in their diet but remain deficient may need to take the next step and get extra vitamin B12 through other sources

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