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Integrating Molecular Perspectives: Strategies for Comprehensive Multi-Omics Integrative Data Analysis and Machine Learning Applications in Transcriptomics, Proteomics, and Metabolomics

Cell Biochem Biophys 84 , 7598 (2026)

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Preclinical animal studies further validate its neuroprotective potential: phillyrin A improves learning and memory in senescence-accelerated mice, activates the Nrf2 signaling pathway in APP/PS1 mice, upregulates antioxidant proteins (NQO1, GPX4), and normalizes cerebral iron content through modulation of TFRC, DMT1, FTH, and FTL gene expression (234)