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Animals were housed in rooms with a relative humidity range of 30-70% and temperature of 6479 o F under a 12 h light/12 h dark cycle with ad libitum access to food and water

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Clin Pharmacol Ther 2022;112:461-84

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Mutation in MTHFR C677T would lead to serum hyperhomocysteinemia by a 50% reduction in MTHFR activity (57)

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